Thrombogenic responses from electrocured tissue adhesives

Himansu Sekhar Nanda; Manisha Singh; Terry W.J. Steele

doi:10.1149/07711.0547ecst

Thrombogenic responses from electrocured tissue adhesives

Himansu Sekhar Nanda, Manisha Singh, Terry W.J. Steele^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

13 Citations (Scopus)

Abstract

Electrocured tissue adhesives offer a new route towards addressing unmet surgical challenges in tissue fixation. We have recently developed an electrocuring adhesive (aka Voltaglue) by grafting carbene precursors on polyamidoamine (PAMAM) G5 dendrimers. The cationic adhesive can be cured through low-voltage activation and exhibits voltage and time dependent crosslinking, allowing some control over material and adhesive properties. Herein, we have evaluated the platelet adhesion and activation of the bioadhesives electrocured with applied voltages of 5V and 10V. The electrocured bioadhesives exhibited platelet resistant properties that was dependent on voltage magnitude.

Original language	English
Title of host publication	Selected Proceedings from the 231st ECS Meeting New Orleans, LA - Spring 2017
Publisher	Electrochemical Society Inc.
Pages	547-555
Number of pages	9
Edition	11
ISBN (Electronic)	9781607688174
ISBN (Print)	9781623324605
DOIs	https://doi.org/10.1149/07711.0547ecst
Publication status	Published - 2017
Externally published	Yes
Event	231st ECS Meeting - New Orleans, United States Duration: May 28 2017 → Jun 1 2017

Publication series

Name	ECS Transactions
Number	11
Volume	77
ISSN (Print)	1938-6737
ISSN (Electronic)	1938-5862

Conference

Conference	231st ECS Meeting
Country/Territory	United States
City	New Orleans
Period	5/28/17 → 6/1/17

Bibliographical note

Publisher Copyright:
© The Electrochemical Society.

ASJC Scopus Subject Areas

General Engineering

Access to Document

10.1149/07711.0547ecst

Cite this

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title = "Thrombogenic responses from electrocured tissue adhesives",

abstract = "Electrocured tissue adhesives offer a new route towards addressing unmet surgical challenges in tissue fixation. We have recently developed an electrocuring adhesive (aka Voltaglue) by grafting carbene precursors on polyamidoamine (PAMAM) G5 dendrimers. The cationic adhesive can be cured through low-voltage activation and exhibits voltage and time dependent crosslinking, allowing some control over material and adhesive properties. Herein, we have evaluated the platelet adhesion and activation of the bioadhesives electrocured with applied voltages of 5V and 10V. The electrocured bioadhesives exhibited platelet resistant properties that was dependent on voltage magnitude.",

author = "Nanda, {Himansu Sekhar} and Manisha Singh and Steele, {Terry W.J.}",

note = "Publisher Copyright: {\textcopyright} The Electrochemical Society.; 231st ECS Meeting ; Conference date: 28-05-2017 Through 01-06-2017",

year = "2017",

doi = "10.1149/07711.0547ecst",

language = "English",

isbn = "9781623324605",

series = "ECS Transactions",

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booktitle = "Selected Proceedings from the 231st ECS Meeting New Orleans, LA - Spring 2017",

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}

Thrombogenic responses from electrocured tissue adhesives. / Nanda, Himansu Sekhar; Singh, Manisha; Steele, Terry W.J.
Selected Proceedings from the 231st ECS Meeting New Orleans, LA - Spring 2017. 11. ed. Electrochemical Society Inc., 2017. p. 547-555 (ECS Transactions; Vol. 77, No. 11).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Singh, Manisha

AU - Steele, Terry W.J.

PY - 2017

Y1 - 2017

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AB - Electrocured tissue adhesives offer a new route towards addressing unmet surgical challenges in tissue fixation. We have recently developed an electrocuring adhesive (aka Voltaglue) by grafting carbene precursors on polyamidoamine (PAMAM) G5 dendrimers. The cationic adhesive can be cured through low-voltage activation and exhibits voltage and time dependent crosslinking, allowing some control over material and adhesive properties. Herein, we have evaluated the platelet adhesion and activation of the bioadhesives electrocured with applied voltages of 5V and 10V. The electrocured bioadhesives exhibited platelet resistant properties that was dependent on voltage magnitude.

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Thrombogenic responses from electrocured tissue adhesives

Abstract

Publication series

Conference

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

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