Tin- and indium-mediated allylation reactions in water: Highly stereoselective synthesis of β-trifluoromethylated homoallylic alcohols

Teck Peng Loh*, Xu Ran Li

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

The indium-mediated allylation reaction of aldehydes with 4-bromo- 1,1,1-trifluoro-2-butene in water afforded β-trifluoromethylated homoallylic alcohols in high yields. In most cases, high regio- and excellent diastereoselectivities were obtained.

Original languageEnglish
Pages (from-to)1893-1899
Number of pages7
JournalEuropean Journal of Organic Chemistry
Issue number8
DOIs
Publication statusPublished - Aug 1999
Externally publishedYes

ASJC Scopus Subject Areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Keywords

  • 1,1,1-Trifluoro-4-bromobut-2-ene
  • Aldehydes
  • Allylation
  • Indium
  • Tin
  • Water

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