Enantioselective bromolactonization of cis-1,2-disubstituted olefinic acids using an amino-thiocarbamate catalyst

Chong Kiat Tan; Chencheng Le; Ying Yeung Yeung

doi:10.1039/c2cc31148h

Enantioselective bromolactonization of cis-1,2-disubstituted olefinic acids using an amino-thiocarbamate catalyst

Chong Kiat Tan, Chencheng Le, Ying Yeung Yeung^*

^*Corresponding author for this work

National University of Singapore

Research output: Contribution to journal › Article › peer-review

115 Citations (Scopus)

Abstract

A facile, highly regio- and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1,2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.

Original language	English
Pages (from-to)	5793-5795
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	46
DOIs	https://doi.org/10.1039/c2cc31148h
Publication status	Published - May 14 2012
Externally published	Yes

ASJC Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "A facile, highly regio- and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1,2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.",

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AU - Tan, Chong Kiat

AU - Le, Chencheng

AU - Yeung, Ying Yeung

PY - 2012/5/14

Y1 - 2012/5/14

N2 - A facile, highly regio- and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1,2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.

AB - A facile, highly regio- and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1,2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.

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Enantioselective bromolactonization of cis-1,2-disubstituted olefinic acids using an amino-thiocarbamate catalyst

Abstract

ASJC Scopus Subject Areas

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