Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding

Franklin L. Zhong*, Kim Robinson, Daniel Eng Thiam Teo, Kiat Yi Tan, Chrissie Lim, Cassandra R. Harapas, Chien Hsiung Yu, William H. Xie, Radoslaw M. Sobota, Veonice Bijin Au, Richard Hopkins, Andrea D’Osualdo, John C. Reed, John E. Connolly, Seth L. Masters, Bruno Reversade

*Corresponding author for this work

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Immunology and Microbiology

Keyphrases

Biochemistry, Genetics and Molecular Biology